Searchable abstracts of presentations at key conferences in endocrinology

ea0026p240 | Pituitary | ECE2011

Detection of antipituitary antibodies using human and primate pituitary glands in patients with autoimmune thyroid disease and diabetes mellitus type 1

Srbova Libuse , Nikolov Hadzi , Cap Jan

Lymphocytic hypophysitis is a rare endocrine autoimmune disorder. Principal laboratory markers for diagnosis are antipituitary antibodies (APA). So far there are no standardized methods for the detection of APA and it is not completely clear which antigens are they targeted to as well. At present the indirect immunofluorescence technique is commonly used for their detection. For this purpose cryostat sections of pituitary gland are used. Commercially accessible sections are ac...